Local Directions: Take Route 68 East, 17 miles to downtown Salinas. Continue through Oldtown to One Main Street. From San Francisco And San Jose: Take 101 South to the Salinas Main Street exit. Continue on North Main to 3rd light. The Center is on the left. From Los Angeles And Points South: Take 101 north to John St. exit. Turn left on John St. to South Main. Turn right on South Main and continue 5 blocks to the Center. Yahoo Maps